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It acts to restore equilibrium between aqueous humor production and outflow Alphagan eye drops lower the pressure in the eye by decreasing the fluid produced and helping the flow of fluid out of the eye chamber. Alphagan comes as eyedrops Brimonidine eye drops are thought to work by reducing the amount of fluid that you make in the front part of your eye (called aqueous humour) and by increasing the drainage of fluid from your eye. When used as directed, brimonidine eye drops have the action of reducing elevated IOP Brimonidine is in a class of drugs called alpha adrenergic agonists. [1] [2] Common side effects when used in the eyes include itchiness, redness, and a dry mouth. Alphagan is used to treat glaucoma, a condition that increases pressure in the eye and leads to vision loss. Sometimes, more than one type of eye drop is needed to keep the pressure in the eye low Alphagan eye drops lower the pressure in the eye by decreasing the fluid produced and helping the flow of fluid out of the eye chamber. 2% in irritated eyes of healthy volunteers as well as patients with glaucoma or ocular hypertension (N=20) in a 2-week, single-center, randomized, double-masked, crossover study Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. Use brimonidine eye drops at around the same times every day, and try. It is usually instilled in the affected eye (s) three times a day. What is Alphagan® Brimonidine Tartrate 0.