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Coadministration with antibiotics decreases efficacy by altering colonic bacterial flora needed to convert sodium picosulfate to active drug. For the treatment of purulent skin infections, such as furunculosis, carbuncle, and skin abscesses. The usual adult dose is 250 mg every 6 hours. Check with your doctor or pharmacist if you are not sure. The 750 mg strength should be administered such that the daily dose is within 1 to 4 grams per day. Do not use Keflex for prophylaxis against the UTI even if you take it in high or low doses because that will yield the same results which is bacterial resistance and maybe the recurrence of the UTI fever, weakness; or. Pediatric Patients (over 1 year of age). With two doses per day, your dog will consume a total of 30 mg/kg of cephalexin over 24 hours of treatment. Keflex 500 MG Capsule is an antibiotic used to treat bacterial infections in different parts of your body including the skin, bone, ears, throat, lungs, and urinary tract. 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